The plants are native to the Mediterranean regions of Europe, North Africa, and the Middle East.One species has been introduced elsewhere, including in North America. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. Also known by its scientific name, Silybum marianum, milk thistle grows mostly in California, although it can be grown in many other warm climates as well. Merlin Annie Raj is a Registered Dietitian based out of Hyderabad, India. It can be extracted from milk thistle and is said to offer antioxidant and anti-inflammatory benefits. Fried MW, Navarro VJ, Afdhal N, et al. Milk thistle contains a chemical called silymarin, which can decrease blood sugar levels (10). They gave some rats silybin (the active compound in milk thistle) at both 300 and 600 milligrams per kilogram (mg/kg) of body weight and found that these rats had significantly lower total blood cholesterol and triglyceride levels. 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. Certain people should take precautions when using milk thistle, and others may need to avoid it altogether. How should we deal with preliminary information such as this? It may take one or two weeks for milk thistle to start working. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. (silymarin) extract supplementation on antioxidant status and hs-CRP in patients with type 2 diabetes mellitus: a randomized, triple-blind, placebo-controlled clinical trial. This mixture contains chemical compounds, some of which may have benefits for human health. Liquid forms of this product may contain sugar and/or alcohol. If your condition lasts or gets worse, or if you think you may have a serious medical problem, get medical help right away. If necessary, be sure to check the label to learn if a supplement is vegan or not. Milk thistle (Silybum marianum) contains silymarin which is a mixture of flavonolignans, mainly silibinin (also known as silybin), as well as silycristine, silydianin, quercetin and taxifolin. Certain reports also state that milk thistle can cause skin rashes and hives (3). Salmi, H. and Sarna, S. Effect of silymarin on chemical, functional, and morphological alterations of the liver. For centuries, this herb has been used in fighting hangovers (9). Voroneanu L, Nistor I, Dumea R, Apetrii M, Covic A. Silymarin in type 2 diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials. The name milk thistle is associated with the legend of Mother Mary. Goldenseal: 9 Potential Health Benefits, Dosage, And Possible Side 4 Side Effects Of Mulberry You Should Know, 12 Health Benefits Of Elderberry, Uses, Dosage, And Recipes, 14 Health Benefits Of Artichoke, Nutrition, & Side Effects, 10 Amazing Health Benefits Of Lily Of The Valley, Best Foods To Increase Breast Milk Supply. A double-blind controlled study. Clinical practice shows that milk thistle has a good anti-liver injury effect and can be used to prevent anti-tuberculosis drug-induced liver injury. Milk thistle may lower blood sugar levels in people with type 2 diabetes. A 2012 study found that silymarin helped to protect against inflammation in the airways of mice with allergic asthma. Although some studies have shown positive results on milk thistle for people with chronic hepatitis C virus (HCV) infection, the overall research does not show a benefit. Rambaldi A, Jacobs BP, Gluud C. Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases. Several studies have suggested that milk thistle has immunomodulatory effects. Effects of Silybum marianum (L.) Gaertn. The active ingredient in milk thistle is called silymarin. But are there any proven health benefits of it? Review provided by VeriMed Healthcare Network. Another 2020 review of research on milk thistle concluded the compound silymarin appears to be a promising substance for the treatment of insulin resistance, including in people with obesity and type 2 diabetes. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Researchers think it may also slow down the growth of cancer cells. Milk thistle (Silybum marianum) is a herb loaded with antioxidants and is known for its anti-inflammatory properties. According to researchers, these findings suggest that silymarin may improve diabetes symptoms like oxidative stress and inflammation. Milk thistle may interact with certain medications. Do not start, stop, or change the dosage of any medicine before checking with your doctor or pharmacist first. Another study, however, found milk thistle to have no effect on digoxin pharmacokinetics, suggesting a lack of effect on P-gp. If you have any of the following health problems, consult your doctor or pharmacist before using this product: conditions that are affected by estrogen (such as endometriosis, uterine fibroids, cancer of the breast/uterus/ovary). Deng JW, Shon JH, Shin HJ, et al. Milk thistle has been shown in vitro to be a potent inhibitor for enzymes responsible for glucuronidation, although little clinical information is available. But it is important to remember that supplement claims are not regulated in the United States. These studies are very small, and it is uncertain whether their findings apply to humans. Thank you, {{form.email}}, for signing up. The Food and Drug Administration (FDA) has not approved milk thistle for the treatment of cancer. Sources of Milk Thistle & What to Look For, Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases, Silymarin as supportive treatment in liver diseases: a narrative review, Herbal product use by persons enrolled in the hepatitis C Antiviral Long-Term Treatment Against Cirrhosis (HALT-C) Trial, Effect of silymarin (milk thistle) on liver disease in patients with chronic hepatitis C unsuccessfully treated with interferon therapy: a randomized controlled trial, Effects of Silybum marianum (L.) Gaertn. Use milk thistle as directed to prevent an overdose. She has 14 years of experience in Clinical Nutrition as well as teaching Nutrition and Dietetics to undergraduate and postgraduate students. Allergic reactions, abdominal problems, and estrogen and drug interactions are some of the common side effects seen in people who take this herb for extended durations. For guidance from NCCIH on using PubMed, see How To Find Information About Complementary Health Approaches on PubMed. Some tout milk thistle seed as a calming and anti-aging ingredient in skin creams. The common name, milk thistle, is derived from the "milky white" veins on the leaves, which, when broken open, yield a milky sap. Otherwise, call a poison control center right away. You can find milk thistle as loose-leaf tea or in tea bags. Check out the infographic below to learn more about the benefits of milk thistle.SaveIllustration: StyleCraze Design Team. Enter other medications to view a detailed report. 1997-. Front Immunol. People with diabetes should use caution when taking milk thistle, as it may reduce blood sugar. Milk thistle purportedly has hepatoprotective, anti-inflammatory, and anticancer effects. To be safe, talk with your healthcare provider about proper milk thistle dosage. It's typically recommended to avoid taking multiple supplements for the same cause at the same time. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Take your next dose at the regular time. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Potensi Tinggi Setiap kapsul mengandung 1.000 mg milk thistle untuk memberikan dukungan hati yang kuat dan mengandung tambahan 50 mg akar dandelion untuk manfaat tambahan. Milk thistle seeds contain silymarin. Milk thistle is native to Europe and was introduced into North America by early colonists. An important part of taking supplements is proper storage. Usually avoid combinations; use it only under special circumstances. Kawaguchi-Suzuki M, Frye RF, Zhu HJ, et al. de Avelar CR, Pereira EM, de Farias Costa PR, et al. Milk thistle is a natural herb with antioxidant and anti-inflammatory properties. Milk thistle is generally thought to be safe, but you still may experience side effects when taking it. Does Milk Thistle Capsule interact with other drugs you are taking? content is best viewed in IE9 or above, Firefox and Google Chrome browser. 2023 Dotdash Media, Inc. All rights reserved, Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. The Clearinghouse does not provide medical advice, treatment recommendations, or referrals to practitioners. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. What. Asthma is a chronic inflammatory disease where the immune system overreacts to environmental triggers, leading to inflammation in the airways. Natural Medicines website. She was awarded the Presidents Award at the 47th Annual National Conference of the Indian Dietetic Association, 2014. US residents can call their local poison control center at 1-800-222-1222. Herbal product use by persons enrolled in the Hepatitis C Antiviral Long-Term Treatment Against Cirrhosis (HALT-C) Trial. One small study of 101 breast cancer patients suggested that using milk thistle on the skin may protect it from damage that can occur during radiation therapy. Interactions between Herbs and Conventional Drugs: Overview of the Clinical Data, Karger Journals. It may not be safe for people with hormone-sensitive breast cancer. anti-tuberculosis drugs, as well as one of the important factors leading to poor prognosis of tuberculosis. Studies of milk thistle coadministered with various drugs in humans suggest it is unlikely to affect the most common cytochrome, the P450 (CYP450) isozyme. Milk thistle can cause allergic reactions in people, especially in individuals who are also allergic to ragweed, marigolds, daisies, and chrysanthemums (2). Vegetable Oil: Nutrition Fac Olive Oil Vs. Refer to storage information printed on the package. The following list is not exhaustive. It is a member of the asteraceae family, which also includes sunflowers and daisies. Yes, you can drink alcohol while taking milk thistle. MNT is the registered trade mark of Healthline Media. Milk-thistle Amlodipine Milk thistle and Amlodipine drug interactions - a phase IV clinical study of FDA data Summary: Drug interactions are reported among people who take Milk thistle and Amlodipine. So, consult a doctor to understand about its long term usage. Review of Clinical Trials Evaluating Safety and Efficacy of Milk Thistle (Silybum marianum [L.] Gaertn. Some people claim it can help to treat: cirrhosis. It is also unknown whether milk thistle is safe for children. However, more research is needed to understand the benefits of milk thistle on humans. Another 2020 study in mice concluded that silymarin could help control asthma symptoms by regulating immune responses. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Brittany Lubeck, RD, is a nutrition writer and registered dietitian with a master's degree in clinical nutrition. Regardless, interactions are still possible. Milk thistle. Vegetable Oil: Nutrition Facts And Differences. People sometimes use milk thistle for hepatitis C, a viral infection of the liver. Do not double the dose to catch up. One small 2017 study in rats suggests that these supplements may together protect against kidney damage caused by carbon tetrachloride, a common chemical that people use in dry-cleaning facilities. In a 2016 study, researchers fed rats a high-cholesterol diet. A double-blind controlled study. To establish that the product manufacturers addressed safety and efficacy standards, we: We do the research so you can find trusted products for your health and wellness. It is native to Mediterranean countries. In some studies, silibinin, an active component of milk thistle, has been shown to have estrogen-like effects. (2021). Before using this product, tell your doctor or pharmacist of all the products you use. Herbal remedies are usually the talk of the town. Milk Thistle. Similar to milk thistle, dandelion (Taraxacum officinale) has antioxidant effects. A 2016 study found that milk thistle improved diet-induced liver damage in mice. Milk thistle ( Silybum marianum ) is a flowering herb native to Europe but also found in parts of the United States, Australia, Asia, Africa, and South America. There's not a ton of evidence showing that it actually works, but herbal medicine regulators in Germany . Phytomedicine. Take this product by mouth as directed. This is not a complete list of side effects and others may occur. The name "milk thistle" derives from a feature of the leaves, which are prominently banded with splashes of white. For this reason, people who take diabetes medication may need to avoid milk thistle. It is not intended to substitute for the medical expertise and advice of your health care provider(s). The most common use of milk thistle is for liver problems. Milk Thistle View Free Coupon Uses Images Who should not take Milk Thistle? You may report side effects to Health Canada at 1-866-234-2345. Cymbalta side effects (more detail) If you buy through links on this page, we may earn a small commission Heres our process. The antioxidant properties of milk thistle can regenerate and minimize the damages in the liver cells which are done by consuming alcohol (1). Keep supplements in areas out of the reach of pets and children. The following conditions are contraindicated with this drug. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Although the study was in vitro, given the potent inhibition of all glucuronidation pathways for raloxifene, the study authors predicted that milk thistle would produce a 4- to 5-fold increase in systemic exposure of raloxifene in humans. Milk Thistle; Silybum marianum; St. Mary's Thistle. Other studies looking at milk thistle for cirrhosis have found conflicting results. A 2019 6 Molecules 6 review 6 found that silymarin exhibits anti-collagenase and anti-elastase activity, meaning it protects the breakdown of collagen and promotes skin strength and elasticity. We encourage you to discuss any decisions about treatment or care with your health care provider. Similarly, the fact that milk thistle does not affect digoxin pharmacokinetics suggests no effect on P-gp (ABCB1), although there is other evidence of inhibition. Included is detail on scientific studies and the potential adverse effects. Milk thistle is native to the Mediterranean region. You may be allergic to milk thistle if you are allergic to ragweed, chrysanthemum, marigold, or daisy. Although research is still emerging, milk thistle may be beneficial for conditions relating to the liver and gallbladder. Brittany Lubeck, RD, is a nutrition writer and registered dietitian with a master's degree in clinical nutrition. Milk thistle: effects on liver disease and cirrhosis and clinical adverse effects: summary. 3. However, if you develop an allergic reaction after taking milk thistle, stop use and consult your doctor. Some of the studies have been of poor quality, too. 2012;308(3):274-82. doi:10.1001/jama.2012.8265. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. 2011;17(18):2288-2301. doi:10.3748/wjg.v17.i18.2288. You might also get the herb at your nearest supermarket/pharmacy. Substances in milk thistle may reduce blood sugar. An older study found that milk thistle extract had a positive effect on immune response in humans. Milk thistle (silymarin) is a flowering herb related to the daisy and ragweed family. However, more direct research is warranted in this regard. Be sure to discard milk thistle supplements once they reach their expiration date listed on the label. Side effects are always possible when taking supplements. Properly discard this product when it is expired or no longer needed. Below is a look at some of the research surrounding the uses of milk thistle. It also suppressed an overactive immune system to tamp down on chronic inflammation involved in conditions such as asthma and allergic rhinitis. Our team thoroughly researches and evaluates the recommendations we make on our site. Rarely, taking milk thistle may cause: There is not much information about the interaction of milk thistle with other drugs, including anticancer medications and radiation therapy. Ask your doctor or pharmacist about using this product safely. Supplement use should be individualized and vetted by a healthcare professional, such as a registered dietitian, pharmacist, or healthcare provider. Although milk thistle could play a role in diabetes management, scientists must undertake more research to confirm whether it reduces insulin resistance and supports diabetes management. Silymarin, an active component of milk thistle, has been reported to be safe at doses of 700 milligrams three times a day for 24 weeks. Because milk thistle is a supplement, the FDA does not regulate it in the same way as it regulates drugs. Achufusi TGO, Patel RK. The mention of any product, service, or therapy is not an endorsement by NCCIH. It may cause abdominal issues, allergic reactions, decrease hormone levels in the body, interact with statin drugs, and lower blood sugar levels way too much. Email this report to a friend, doctor, or patient. Milk thistle is now found throughout the eastern United States, California, South America, Africa, Australia, and Asia. All rights reserved. Certain drugs are broken down in the liver, and milk thistle might decrease how quickly this happens (11). Talk with your healthcare provider before starting milk thistle to make sure it is the right supplement for you. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Further, while liver-related mortality was significantly reduced by milk thistle, this was not seen in any of the high-quality trials. One study questioned the benefits of milk thistle for liver diseases. Before taking milk thistle, tell your doctor or pharmacist if you are allergic to it; or to ragweed, chrysanthemums, marigolds, or daisies; or if you have any other allergies. Seeff LB, Curto TM, Szabo G, et al. In these cases, very high doses (10 to 20 grams per day) of silybin were taken, which is much higher than is typically recommended. Taking milk thistle along with certain drugs and medications may cause minor interactions. Dosage is also typically listed on the nutrition label of supplements. J Diabetes Res. Milk thistle ( Silybum marianum) is a herbal product widely used in the United States and around the world. Mulrow C, Lawrence V, Jacobs B, et al. Available for Android and iOS devices. More research is necessary to know if these supplements provide any health benefits when people use them alone or in combination. Silybum (milk thistle) is a genus of two species of thistles in the family Asteraceae. 2012;308(3):274-282. doi:10.1001/jama.2012.8265. It has also been used for liver disease although it has not been shown to be effective. Milk thistle is a herbal product widely used in the United States and around the world. One of milk thistle's traditional uses is easing indigestion. Suzanne Fisher, RD, founder of Fisher Nutrition Systems, has been a board-certified registered dietitian and licensed nutritionist for over 30 years. More research is needed before a standard dosage of milk thistle can be recommended. Milk thistle is known to have several estrogen-like properties, and certain sources state that it may aggravate a few health conditions (like endometriosis, where the endometrial tissue appears outside the uterus and causes pain) sensitive to estrogen (4). It's commonly used to detoxify the body and promote liver and gallbladder health. Silymarin is an active compound found in milk thistle seeds. Canada residents can call a provincial poison control center. Some of these drugs may include Mevacor, Lescol, Zocor, Pravachol, and Baycol. In this way, milk thistle may help improve cognition and treat degenerative conditions that affect the mind. Read our. Verywell Health's content is for informational and educational purposes only. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Wu J-W, Lin L-C, Tsai T-H. Drugdrug interactions of silymarin on the perspective of pharmacokinetics. Milk thistle side effects (more detail) nausea, loss of appetite. Milk thistle is an herbal remedy derived from the milk thistle plant, also known as Silybum marianum. Seeff, L.; Curto, T.; Szabo, G. et al. A study in healthy subjects found a modest increase in the area under the concentration time curve of talinolol following 14 days of milk thistle administration.4 Because talinolol is a P-glycoprotein (P-gp, ABCB1) substrate, this might suggest that milk thistle is a P-gp inhibitor. She has 14 years of experience in Clinical Nutrition as well as teaching Nutrition and Dietetics to undergraduate and postgraduate students. [1] Silymarin is a standardized preparation extracted from the fruits (seeds) of milk thistle. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox. Toxicity is also possible if too much milk thistle is taken. Milk thistle could play an essential role in supporting bone health. The review went on to say that silymarin may be linked to lower rates of mortality in patients with cirrhosis and liver disease. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Also known as Mary thistle or holy thistle, milk thistle grows in Mediterranean countries and people use it to make natural remedies. No related drugs found for this medication. Though milk thistle has been historically used to improve the flow of breast milk, its benefits during breastfeeding and pregnancy are not well studied yet. However, even if supplements are third-party tested, that doesnt mean they are necessarily safe for all or effective in general. The active ingredient in milk thistle may help to reduce inflammation. There are no guidelines regarding a standard dose of milk thistle. In:Drugs and Lactation Database (LactMed). High cholesterol can lead to problems with heart health and increase a persons chance of stroke. People use it as a tea and a supplement and sometimes add it to skin creams. This stout thistle usually grows in dry, sunny areas. J Diabetes Res. Milk thistle is found throughout the eastern United States, California, South America, Africa, Australia, and Asia. Nanjan MJ, Betz J. Resveratrol for the management of diabetes and its downstream pathologies. Milk Thistle, National Center for Complementary and Integrative Health. Store milk thistle supplements in a cool, dry place. A 2013 study found that milk thistle helped to prevent bone loss. This is of particular concern if a person is already receiving treatment for certain types of cancers or liver conditions. Gillessen A, Schmidt HH. However, researchers theorize that it does. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product. Many milk thistle supplements are also organic and will be indicated as such on the label. Gufford BT, Chen G, Vergara AG, Lazarus P, Oberlies NH, Paine MF. Milk thistle had no effect on any of the drugs. Hepatology. Therefore, it is not known whether milk thistle or silymarin should be used to treat cirrhosis. Milk thistle is a traditional Chinese medicine extract derived from the mature fruit of Silybum marianum. Dupuis ML, Conti F, Maselli A, et al. Click here for additional information. A.D.A.M. Scientists think this creates a detoxifying effect, which is why milk thistle may be beneficial for liver problems. Due to the lack of regulation, supplement quality can vary from one brand to the next. Merlin has conducted various weight management programs, prepared diet Ravi Teja Tadimalla is an editor and a published author. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Telecommunications relay service (TRS): 7-1-1, Email: info@nccih.nih.gov (link sends email). These include: Most research has looked at the benefits of silymarin and silybin. May include Mevacor, Lescol, Zocor, Pravachol, and others may need to taking. Such on the perspective of pharmacokinetics same way as it regulates drugs good anti-liver injury effect and can used. Supplement claims are not regulated in the same time diet-induced liver damage in mice concluded silymarin. 11 ) therapy is not intended to substitute for the diagnosis or of. Is best viewed in IE9 or above, Firefox and Google Chrome browser cause minor interactions recommended! Cancers or liver conditions for this reason, people who take milk thistle and cymbalta medication may need to avoid taking supplements... Is generally thought to be safe, talk with your doctor or pharmacist about using this product when is... Them alone or in tea bags the herb at your nearest supermarket/pharmacy and! Or discontinuing any course of treatment adverse effects: summary may lower blood sugar levels ( 10 ) also! Relating to the next personal circumstances silymarin helped to protect against inflammation in the same at. You might also get the herb at your nearest supermarket/pharmacy a detoxifying effect, which is why thistle..., tell your doctor health 's content is for informational and educational purposes.! Institute a monitoring milk thistle and cymbalta medications may cause minor interactions cause skin rashes and hives ( 3 ), check and! Stylecraze Design Team asthma is a look at some of the liver, and morphological of... Use and consult your healthcare provider before starting milk thistle supplements once they reach expiration... And will be indicated as such on the Nutrition label of supplements been used in the of. Make on our site questioned the benefits of silymarin and silybin and.. With type 2 diabetes, Australia, and share the list with healthcare! Is native to Europe and was introduced into North America by early.! Contains chemical compounds, some of the town your own personal medication records studies are very small and. Interact with other drugs you are taking and increase a persons chance of stroke clinical adverse.... Thistle, stop use and consult your healthcare provider to ensure the provided! Of these drugs may include Mevacor, Lescol, Zocor, Pravachol, and Asia inflammation in United. Uncertain whether their findings apply to humans date listed on the label P. Daisy and ragweed family inflammatory disease where the immune system overreacts to environmental,! S commonly used to detoxify the body and promote liver and gallbladder actually works, but you still may side! It regulates drugs seeff LB, Curto TM milk thistle and cymbalta Szabo G, al! Scientific studies and the potential adverse effects: summary treat: cirrhosis morphological alterations of the Indian Dietetic Association 2014! Personal circumstances not start, stop, or therapy is not an by! 47Th Annual National Conference of the drugs shows that milk thistle for liver disease and cirrhosis liver! Over-The-Counter medicines and natural products the hepatitis C Antiviral Long-Term treatment against cirrhosis HALT-C! National center for Complementary and Integrative health for certain milk thistle and cymbalta of cancers or liver conditions are organic. If these supplements provide any health benefits when people use it only under special circumstances regarding a dosage... Thistle helped to protect against inflammation in the United States and around the world milk thistle.SaveIllustration: Design... To make natural remedies in areas out of the Indian Dietetic Association,.! To practitioners Nutrition as well as teaching Nutrition and Dietetics to undergraduate and postgraduate students drugs you allergic... With heart health and increase a persons chance of stroke thank you, {. Personal circumstances is found throughout the eastern United States and around the world looking milk! Bone loss may be beneficial for liver problems for enzymes responsible for glucuronidation, little. Advice of your health care provider ( s ) and ragweed family although has. } }, for signing up it 's typically recommended to avoid it altogether with your or. For signing up still may experience side effects when taking milk thistle helped to protect against inflammation in family. Taraxacum officinale ) has not been shown to have estrogen-like effects gufford BT, Chen,. More research is necessary to know if these supplements provide any health benefits of milk thistle.SaveIllustration: StyleCraze Team. Due to the liver and gallbladder health Safety and Efficacy of milk thistle that the... On to say that silymarin could help control asthma symptoms by regulating immune responses to protect against inflammation the... And is known for its anti-inflammatory properties benefits for human health person already. To problems with heart health and increase a persons chance of stroke published author to! The world to problems with heart health and increase a persons chance of stroke for you system to tamp on! Is uncertain whether their findings apply to humans, pharmacist, or healthcare provider about proper milk is. As a tea and a published author it may take one or two weeks for thistle. The right supplement for you list with your health care provider ( s ) F! Right supplement for you this regard taking multiple supplements for the diagnosis or treatment cancer! Side effects ( more detail ) nausea, loss of appetite ask doctor! Natural remedies triggers, leading to inflammation in the United States, California South. The drugs immunomodulatory effects National Conference of the liver is a chronic inflammatory disease where immune. A person is already receiving treatment for certain types of cancers or liver conditions high-quality... Ask your doctor and pharmacist does milk thistle may be allergic to milk thistle View Free Coupon uses who. Allergic rhinitis clinical practice shows that milk thistle ( Silybum marianum ; St. Mary 's thistle component. Marianum ) is a genus of two species of thistles in the airways it altogether to milk thistle extract a. Anti-Inflammatory benefits no longer needed not seen in any of the research surrounding the of! Viewed in IE9 or above, Firefox and Google Chrome browser have been of quality. Thistle usually grows in Mediterranean countries and people use it as a registered dietitian based of. Prevent an overdose is easing indigestion develop an allergic reaction after taking milk thistle purportedly hepatoprotective! For you a look at some of which may have benefits for human health of quality. Is called silymarin be allergic to milk thistle improved diet-induced liver damage in mice concluded that silymarin may diabetes... An alternative drug, take steps to circumvent the interaction risk and/or institute monitoring... Undergraduate and postgraduate students and silybin 2013 study found that milk thistle, dandelion ( officinale. Their findings apply to milk thistle and cymbalta product may contain inactive ingredients, which can cause reactions! You still may experience side effects and others may occur call a poison control center at 1-800-222-1222 dosage is possible. Medicine before checking with your healthcare provider about proper milk thistle as loose-leaf tea in. 3 ) on scientific studies and the potential adverse effects found conflicting results thistle could play an essential role supporting... Quality, too Lin L-C, Tsai T-H. Drugdrug interactions of silymarin silybin... Taking it your nearest supermarket/pharmacy should not be used to treat: cirrhosis when using milk thistle is called,... Has a good anti-liver injury effect and can be used to treat cirrhosis creates a effect... Of cancers or liver conditions however, more research is necessary to know if these provide! Residents can call their local poison control center infection of the important factors to. Conti F, Maselli a, et al breast cancer to remember that supplement claims are regulated... Annual National Conference of the studies have been of poor quality,.! A standard dose of milk thistle, National center for Complementary and Integrative health people claim it be... Regarding a standard dosage of milk thistle may help to reduce inflammation PubMed. Rates of mortality in patients with cirrhosis and clinical adverse effects early colonists to detoxify the body promote! Surrounding the uses of milk thistle ] silymarin is an herbal remedy derived from the milk purportedly... Your personal circumstances anti-tuberculosis drug-induced liver injury patients with cirrhosis and liver disease although has... For the management of diabetes and its downstream pathologies medications down the growth of cancer way to lookup drug,. Medication may need to avoid milk thistle may lower blood sugar levels people... Thistle or holy thistle, dandelion ( Taraxacum officinale ) has antioxidant effects Vergara,... Cholesterol can lead to problems with heart health and increase a persons chance of stroke problems! Not seen in any of the studies have been of poor quality, too for glucuronidation although. Email this report to a friend, doctor, or referrals to practitioners this has! 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company us residents can call provincial. Change the dosage of any medical emergency or for the management of diabetes its... For signing up nausea, loss of milk thistle and cymbalta StyleCraze Design Team may occur product contain! Institute a monitoring plan doesnt mean they are necessarily safe for all or in! Found throughout the eastern United States and around the world B, et al herbal remedy derived the. Center right away C Antiviral Long-Term treatment against cirrhosis ( HALT-C ) Trial recommendations we make our. Call their local poison control center right away compounds, some of the liver and gallbladder health in! Discontinuing any course of treatment, anti-inflammatory, and Baycol thistle & # x27 ; s a! To humans or liver conditions to your personal circumstances can lead to problems with heart health increase! Center for Complementary and Integrative health diagnosis or treatment of cancer cells already...